Glutamate and Cocaine Addiction

A Double-Blind, Placebo-Controlled Trial Of Modafinil For …
Keywords: modafinil; cocaine; glutamate; pharmacotherapy; abstinence; addiction INTRODUCTION Cocaine dependence is a major public health problem that … View Full Source

Neurobiology Of Cocaine Addiction
Neurobiology of Cocaine Addiction Neural Level N accumbens, tegmentum, extended amygdala, neocortex Molecular Level Dopamine, DAT, Noradrenalin, Serotonin, SERT, Glutamate, CART, … Read Document

The Official Journal Of The American Academy Of Addiction …
Cystine=glutamate exchange regulates metabotropic glutamate receptor presynaptic inhibition of excitatory transmission and vul-nerability to cocaine seeking. J Neurosci. 2005;25:6389–6393. 30. Goldstein RA, Volkow ND. Drug addiction and its underlying neu- … Access Document

Glutamate Systems In cocaine addiction
Glutamate systems in cocaine addiction Peter W Kalivas All addictive drugs facilitate dopamine transmission, and determining the role of dopamine has been the predominant … Read Here

Cocaine Inverts Rules For Synaptic Plasticity Of glutamate …
2011 Nature America, Inc. All rights reserved. nature neuroscience advance online publication Brief communications A widely accepted hypothesis posits that addictive drugs hijack learn- … Retrieve Doc

Glutamate Receptors On Dopamine Neurons Control The …
Neuron Article Glutamate Receptors on Dopamine Neurons Control the Persistenceof Cocaine Seeking David Engblom, 1 , 7 , 9 Ainhoa Bilbao, 2 , 7 Carles Sanchis-Segura, 2 , 7 , 10 Lionel Dahan, 3 , 7 Ste ´ phaniePerreau-Lenz, 2 Be ´ ne ´ dicteBalland, 3 Jan Rodriguez Parkitna, 1 Rafael Luja ´ n … View Doc

The Blaylock Wellness Report
And glutamate levels in the brain. Thus, blocking glutamate receptors can prevent cocaine addiction and its accompanying cravings. Likewise, studies … Read Here

Group I Metabotropic Glutamate Receptors: Involvement In Drug …
Keywords: Metabotropic glutamate receptor, reward, motivation, dependence, addiction, ethanol, cocaine. INTRODUCTION Addiction in Society Addiction to drugs of abuse is a leading health problem in Western society. … Retrieve Content

Program#/Poster#: 346.14 / U8
Neuronal glutamate release (called glutamate homeostasis). Currently, there is no approved treatment for cocaine addiction. Our results suggest that N- … Fetch Content

Psychomotor Stimulant Addiction: A Neural Systems Perspective
Cornish JL, Kalivas PW (2000) Glutamate transmission in the nucleus accumbens mediates relapse in cocaine addiction. J Neurosci 20:1–5. Cornish JL, Duffy P, Kalivas PW (1999) A role for nucleus accumbens … Fetch Doc

TRADITIONAL POSTER
13C MRS uniquely quantifies glutamine-glutamate cycle rate in either neurons or glia, driven by the substrate selection of their cellular membrane transporters. … View This Document

Reversing cocaine-induced Synaptic Potentiation Provides …
The potential clinical utility of a strategy to restore glutamate homeostasis in treating cocaine addiction. The pro?le of physiological responses normalized by N- … Doc Retrieval

Drug Addiction
Treat Addiction –Using Glutamate Homeostasis to Robert Malcolmand SteveLaRowe dependence. †† Tri-weekly urine measurements to verify NAC and cocaine use … Doc Viewer

Neuron, Vol. 45, 647–650, March 3, 2005, Copyright ©2005 …
Fects of acute drug administration and how drug use underlie the pathophysiology of cocaine addiction: do-may transition from regulated (social) to compulsive pamine synapses in the PFC and glutamate synapses … Retrieve Document

Neuropharmacology Of addiction
Keywords Extendedaccumbens; addiction; alcohol; amygdala; cocaine; dopamine; ecstasy; glutamate; neuropharmacology; nicotine; opioid; orbitofrontal; withdrawal Although psychological theories of addiction predominate and … Return Doc

Glutamate Transmission In The Nucleus Accumbens Mediates …
Glutamate Transmission in the Nucleus Accumbens Mediates Relapse in Cocaine Addiction JenniferL. Cornishand Peter W. Kalivas Department of Physiology and Neuroscience, Medical University of South Carolina, Charleston, South Carolina 29425 Elevated dopamine transmission in the nucleusaccumbens is … Return Doc

Brain Glutamate Concentrations Affect Cocaine Seeking
cocaine and other drug abuse and addiction. Glutamate signals also amplify the addictive effects of nico-tine (see “Nicotine’s Multiple Effects … Get Doc

The New Science Of Addiction: Genetics And The Brain Mouse Party
The New Science of Addiction: Genetics and the Brain Methamphetamine Alcohol Cocaine LSD Dopamine Dopamine Serotonin GABA Glutamate Taken up by dopamine transporters … Access Full Source

Glutamate Systems In cocaine addiction Peter W Kalivas
Glutamate systems in cocaine addiction Peter W Kalivas All addictive drugs facilitate dopamine transmission, and determining the role of dopamine has been the predominant … Access Doc

Brain-derived Neurotrophic Factor and Cocaine addiction
Glutamate systems in cocaine addiction. Curr. Opin. Pharmacol. 4,23-29. Kalivas, P.W., Volkow, N.D., 2005. The neural basis of addiction: a pathology of motivation and choice. … Retrieve Content