Serotonin Cocaine Abuse
A Case Of Mutism Subsequent To Cocaine Abuse
Mon consequence of cocaine abuse because of the spasm of cerebral blood vessels induced by excessive release of catecholamines. In vitro studies have documented that cocaine can block the reuptake of dopamine, serotonin, … Get Content Here
SEROTONIN’S ROLE IN ALCOHOL’S EFFECTS ON THE BRAIN
PONTIERI, F.E.; TANDA, G.; AND DI CHIARA, G. Intravenous cocaine, morphine and amphetamine preferentially increase extracellular abuse: (1) analyses of serotonin levels in alcoholics and nonalcoholics and (2) studies of drugs that block serotonin … View Full Source
NewsScan August 22, 2007 NEWS UPDATE
Dopamine and serotonin releasers may reduce this abuse potential. Finally, the authors identified a compound, PAL287, which potently releases both dopamine and serotonin and found that it reduces cocaine self-administration in animal … Access Document
Drug Fact Sheet
cocaine, the over-the-counter cough suppressant MDMA mainly affects brain cells that use the chemical serotonin to communicate with each other. As with many other drugs of abuse, MDMA is rarely used alone. … View Doc
The Infant Of Drug Dependent Mother
Decreases reuptake of tryptophan ? affecting serotonin biosynthesis Dec serotonin: decreased need for sleep (serotonin regulates sleep-wake cycle) Cocaine generally discouraged if noncompliant Drug-dependent mothers as caregivers Social service referral Potential child abuse Follow … View Document
Cocaine Abuse
These chemicals or neurotransmitters, such as norepinephrine, dopamine, serotonin, acetylcholine, and • Psychiatric problems caused by cocaine abuse may include cocainomania, anxiety, hallucinations, para- … Doc Viewer
Nonhuman Primate Neuroimaging And Cocaine Medication Development
And SERT may be a viable approach to treat cocaine addiction. Keywords: cocaine, dopamine transporter, serotonin transporter, PET imaging, nonhuman primates Despite extensive efforts directed toward the develop-ment of medications to treat cocaine abuse, no effective … View Doc
Muscle Relaxants, Substance Abuse And CNS Stimulants
Muscle Relaxants, Substance Abuse and CNS Stimulants By Linda Self Benzodiazepines Librium, Valium, Versed to enhance absorption and work as an additive with ergots, oxycodone, OTC pain and cold remedies Cocaine Powerful CNS stimulant Prevents reuptake of dopamine, norepinephrine and serotonin and … Retrieve Content
Serotonin Transporter (5-HTT) Targeted Mutation Mouse Model
HTT) that normally removes serotonin from the synaptic cleft and mediates its re-uptake into pre-synaptic neurons. Potential applications of the 5-HTT Targeted Mutation Mouse include: • Clarifying the mechanism of action of drugs of abuse, like cocaine and "ecstasy", and of … Fetch Here
Serotonin And Drug Reward: Focus On 5-HT Receptors 2C
Effects of the serotonin 5-HT(2) antagonist, ritanserin, and the serotonin 5-HT(1A) antagonist, WAY 100635, on cocaine-seek-ing in rats. Pharmacol. Biochem. Behav. 67, 363–369. Sellers, E.M., Higgins, G.A., Sobell, M.B., 1992. 5-HTand alcohol abuse. … Fetch Here
Cocaine Reward Models: Conditioned Place Preference Can Be …
Substantial abuse liability in humans or animal model studies (11–13). Because mazindol potently inhibits dopamine and norepinephrine transport, but only weakly inhibits serotonin transport, this difference from cocaine could conceivably … Fetch Doc
Therapeutic Effects Of Paroxetine On The cocaine abuse In …
Paroxetine, as suggested for other serotonin reuptake inhibitor drugs, may be considered a safe, effective therapeutic agent in treating of cocaine abuse in … Get Document
The Serotonergic System And Its Role In cocaine Addiction
Craving in cocaine addicts [43, 53, 59]. Serotonin implication in long-term cocaine abuse Long-term cocaine abuse leads to addiction (i.e. to compulsive drug taking), mood disturbances, para- … Return Document
Further SAR Studies Of Piperidine-Based Analogues Of Cocaine …
Sive cocaine seeking behavior (craving). Accordingly, 5-HT-based agents are being investigated as possible medications for the treatment of cocaine abuse as well.7 Interestingly, serotonin inhibitors lacking dopaminergic … Retrieve Full Source
Serotonin And Drug Reward: Focus On 5-HT
Effects of the serotonin 5-HT(2) antagonist, ritanserin, and the serotonin 5-HT(1A) antagonist, WAY 100635, on cocaine-seek-inginrats. Pharmacol. Biochem. Behav. 67,363-369. Sellers, E.M., Higgins, G.A., Sobell, M.B., 1992.5-HT and alcohol abuse. … Retrieve Full Source