Role Erk Cocaine Addiction

Liste De Symposium
The molecular mechanisms that participate to cocaine addiction. Dr. Fumagalli (Italy) will show the role of Fabio Fumagalli , Milan, Italy : Stress and cocaine mutually interact to modulate the activation of BDNF intracellular signaling 4. Emmanuel Valjent , Stockholm, Sweden : Role of the ERK … Doc Retrieval

Regulation Of ERK1/2 Phosphorylation By Acute And Chronic …
In the current study, we interrupted signal transduction downstream of ERKs to check the role of feedback-based regulation in ERK activity. Science 278,58-63. 2 Nestler EJ (1997) Molecular mechanisms of opiate and cocaine addiction. … Get Doc

BMC Neuroscience BioMed Central
Role of the ERK pathway in the D-amph- or cocaine-conditioned locomotor response esses are thought to be crucial for human addiction since exposure to environmental stimuli previously associated … Read Content

Role Of Cannabinoid Type 1Receptorsin Locomotor Activity AndS …
LuL, KoyaE, Zhai H, Hope BT, Shaham Y (2006) Role of ERK in cocaine addiction. Trends Neurosci 29:695-703. MaldonadoR, Valverde O, Berrendero F (2006) Involvement of the endo-cannabinoid system in drug addiction. … View Full Source

METABOTROPIC GLUTAMATE RECEPTOR MEDIATED SYNAPTIC PLASTICITY …
The Role of ERK in Group I MGluR LTD KO mice and the effects of chronic cocaine treatment implicate Homer in regulating addiction to cocaine. cocaine, suggesting that alterations in this form of plasticity may play a role in cocaine-induced … Return Doc

BMC Neuroscience
Here, we further investigated the role of JNK signaling at this model synapse employing an A major requirement in long-term plasticity for the ERK/ MAPK (extracellular signal-regulated As suggested by its importance in the control of processes underlying cocaine addiction [29], new data … Access Content

Tissue Plasminogen Activator Modulates The Cellular And …
Lu L, et al. (2006) Role of ERK in cocaine addiction. Trends Neurosci 29(12):695–703. 26. Erb S, Brown ZJ (2006) A role for corticotropin-releasing factor in the long-term … Fetch Content

The Dynorphin/kappa Opioid System As A Modulator Of Stress …
Activation of the ERK 1/2 signal transduction cascade has been A role for brain stress systems in addiction. Neuron 59, 11–34. cocaine seeking in squirrel monkeys: a role for opioid and … Fetch Document

Inhibition Of ERK Pathway Or Protein Synthesis During …
These results suggest potential therapeutic strategies to explore in the context of addiction. cocaine The Effectsof ERK Blockade on Cocaine-or Morphine-Induced CPP Are Mimicked by a Protein Synthesis Inhibitor. … View Full Source

Knockout Of ERK1 Enhances Cocaine-Evoked Immediate Early Gene …
RESULTS Inhibitonof MEK Attenuates Cocaine Psychomotor Sensitization The role of ERK signaling in psychomotor sensitization to cocaine has not been fully circuit represents part of a shared mechanism that mediates forms of drug-induced plasticity that may playa role in the development of addiction … Return Document

The role Of Neuroadaptations In Relapse To Drug Seeking – One …
NATURE NEUROSCIENCE VOLUME 8 | NUMBER 11 | NOVEMBER 2005 1437 NEUROBIOLOGY OF ADDICTION The role of neuroadaptations in amygdala ERK pathway to cocaine cues mediate the incubation of cocaine craving … Get Content Here

MeCP2 Controls BDNF Expression And cocaine Intake Through …
MeCP2 may also function in drug addiction. First, repeated cocaine implications for incubation of cocaine craving. J. Neurosci. 23, 742–747 (2003). 26. Lu, L. et al. Central amygdala ERK signaling pathway A role for BDNF in cocaine reward and relapse. Nat. … Access Full Source

BIOGRAPHICAL SKETCH Darlene H. Brunzell, Ph.D.
Prenatal cocaine effects on context conditioning: exaggeration of sex-dependent context extinction. NIDA Drug Addiction Center Grant, Small Grant Brunzell, D.H. (PI) 04/09-03/10 “The role of ERK and CREB signaling in nicotine dependence.” … Fetch This Document

The addicted Synapse: Mechanisms Of Synaptic And Structural …
Both receptors can also regulate extracellular signal regulated kinase (ERK) cascades. 9,205-211 60 Renthal,W. et al. (2009) Genome-wide analysis of chromatin regulation by cocaine reveals a role Transcriptional mechanisms of addiction: role of DeltaFosB. … Content Retrieval

REGULATION OF COCAINE-INDUCED ACTIVATOR PROTEIN 1 …
Cade for cocaine-rewarding properties. J Neurosci 20:8701–8709. Valjent E, Harve D, Caboche J, Girault JA (2003) Possible role of the extracellular signal-regulated kinase (ERK) in reward-controlled learning and addiction. … Content Retrieval

Incubation Of cocaine Craving:
The neuroadaptation hypothesis of addiction neurochemical adaptations in the mesocorticolimbic dopamine system that underlie Nature Neuroscience , 2004 Role of central amygdala ERK in incubation of cocaine craving … Content Retrieval

Absence Of The GPR37/PAEL Receptor Impairs Striatal Akt And …
The ERK path-way plays a crucial role in the establishment and development of long-lasting behavioral effects of cocaine addiction. Curr. Opin. Neurobiol. 7, 713–719 39. Ghisi, V., Ramsey, A. J., Masri, B., Gainetdinov, R. R., Caron, … Retrieve Content

Parsing Molecular And Behavioral Effects Of Cocaine In …
Cocaine induces ERK-dependent activation of MSK1 in thestriatum ERK cannotphosphorylateCREB directly at Ser 133 because Egr-1 (also termed zif268 , Krox24 ,or NGFI-A ), in the striatumafter acute administration of cocaine is thought to playa key role in the neuronal alterations leading to addiction … Get Doc

NewsScan February 1, 2006 NEWS UPDATE NIDA ADDICTION RESEARCH …
Signal-regulated kinase (ERK) pathway, which has been implicated in the central is needed to better understand the neural pathways and systems involved in cocaine addiction in significant role in drug abuse and addiction through its effects on reward and motivation. … Read Document